WebRabbit Phospho-SHP2-Y542 Rabbit pAb (AP0267), validaed in WB,, IHC and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. Replacement to Abcam, Santa Cruz, Sigma and CST antibody. WebThe expression levels of SHP2 (6D9, 1:500, NOVUS), phospho-SHP2 (pSHP2) (Y542, 1:150, ABCAM), and PD-L1 (E1L3N, 1:200, CST) were assessed using immunohistochem-istry (IHC). The procedures were carried out according to manufacturer’s instructions, and IHC staining was scored based on semiquantitative analyses by two independent …
Human/Mouse Phospho-SHP-2 (Y542) Antibody …
WebPolyclonal Antibody for studying SHP-2 (Tyr546) phosphate. Cited in 82 publications. Validated for Western Blotting, Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, Phospho … WebThe L99-921 monoclonal antibody recognizes the phosphorylated Y542 of SHP2 (PTP2C isoform 2). The homologous phosphorylation site in the PTP2Ci splice variant (isoform 1) is Y546. The specificity of this antibody was validated by confirming, using western blot analysis, that RNA-mediated interference (RNAi) of the specific protein was able to ... gec cat wildman
Src-Homology 2 Domain-Containing Phosphatase 2 in Resected
WebOct 8, 2024 · In summary, these data suggest that phosphorylation of SHP2 at Y542 is associated with disease progression and that this event can be mediated by the ECM in … WebNotably, SHP2 activation was found in KRAS-mutant NSCLC cells with TKIs treatment, as judged by the increase of tyrosine 542 phosphorylation (pSHP2 Y542), which activates the RAS/MEK/ERK pathway. On the … WebSep 3, 2009 · Total cellular protein extracts were then subjected to Western blotting for P-SHP2 Y542 and Y580, total SHP2, and tubulin. Close modal We also compared the effects of M-CSF or G-CSF on the STAT1, STAT3, and STAT5 transcription factors or SHP2, a tyrosine phosphatase that contributes to ERK activation 26 ( Figure 2 C top panel lanes 1 … gec c11b2 meter phase