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Hepatocellularity翻译

Webhepatocellular中文 (简体)翻译：剑桥词典 hepatocellular 在英语-中文（简体）词典中的翻译 hepatocellular adjective medical specialized uk / ˌhep.ə.təʊˈsel.jə.lə r/ us / … Web28 jul. 2016 · The hepatocellularity of the Göttingen minipig was assessed based on the DNA and the protein quantification methods previously used for other species (53,58). For both methodologies, specific amounts of hepatocytes suspension cultures were compared to a specific amount of homogenized liver tissue, assuming that the liver tissue is mainly …

Scaling factors for the extrapolation of in vivo metabolic drug ...

Web7 mrt. 2024 · To accurately predict human clearance, it is essential to understand the clearance mechanisms involved (i.e., hepatic metabolism, hepatic uptake, biliary secretion, or renal clearance), so that appropriate methods can be applied to the predictions. WebWilson ZE, Rostami-Hodjegan A, Burn JL, Tooley A, Boyle J, Ellis SW, Tucker GT. Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver. Br J Clin Pharmacol. 2003 Oct56(4):433-40. abstract PubMed ID 12968989: Method baird wiki https://beadtobead.com

欧路词典 英汉-汉英词典 hepatocellular是什么意思_hepatocellular …

Web1 jul. 2016 · For instance, when hepatocytes are used to predict hepatic drug clearance, the hepatocellularity (number of hepatocytes per gram liver, HPGL) is required as one of … Webhepatocellular的意思、解释及翻译：1. relating to liver cells: 2. relating to liver cells: 。了解更多。 aqua water park

VALUES OF HUMAN HEPATOCELLULARITY PER GRAM OF LIVER …

Category:hepatocellular是什么意思_hepatocellular怎么读_hepatocellular翻 …

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Hepatocellularity翻译

Effect of Age on The Hepatocellularity Number for Wistar rats

WebMean geo hepatocellularity was 163 × 10 6 cells g −1 liver for Wistar rats (95% CI = 127–199 × 10 6 cells g −1 liver) and 169 × 10 6 cells g −1 liver (95% CI = 131–207 × 10 6 cells g −1 liver) for beagle dogs. The data generated in this study indicate a consistency in scaling factors between rat and dog. WebHepatocellularity numbers were calculated from the ratio between the liver protein concentration and the protein concentration in the corresponding hepatocyte suspension. …

Hepatocellularity翻译

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Web1 aug. 1997 · Microsomal protein recovery and hepatocellularity have been determined and investigated as scaling factors for interrelating clearance by hepatic microsomes, freshly isolated hepatocytes and whole liver from untreated (UT) rats and rats treated with either the cytochrome P450 inducer phenobarbital (PB) or dexamethasone (DEX). WebMean(geo) hepatocellularity was 163 x 10(6) cells g(-1) liver for Wistar rats (95% CI = 127-199 x 10(6) cells g(-1) liver) and 169 x 10(6) cells g(-1) liver (95% CI = 131-207 x 10(6) …

WebAims: To determine levels of microsomal protein (MPPGL) and hepatocellularity (HPGL) per gram of human liver and their interindividual variability. Methods: Triplicate liver samples were used to determine values of MPPGL (n = 20) and HPGL (n = 7) after accounting for the fractional loss of microsomal protein or hepatocytes during processing. Webhepatocellularity (3.1×109 cells per kilogram body weight, dotted line in Fig. 1)(27). Similar regression analyses for different datasets found that the empirical scaling factors necessary for accurate predictions were 5.2-fold (35) and 5.6-fold larger (45) than hepatocellularity (2.5–3.1×109 cells per

WebScaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and … Web1 jan. 2007 · Abstract. Reported predictions of human in vivo hepatic clearance from in vitro data have used a variety of values for the scaling factors human microsomal protein (MPPGL) and hepatocellularity (HPGL) per gram of liver, generally with no consideration of the extent of their inter-individual variability. We have collated and analysed data from a ...

Web1. Scaling factor values for the in vitro-in vivo extrapolation of hepatic metabolic clearance for xenobiotics have not yet been determined in horses. Scaling factors were determined …

WebMicrosomal protein per gram of liver (MPPGL) and hepatocellularity number per gram of liver (HPGL) using CYP P450 content method ranged 41–73 mg/gram of liver (mean= 57 … aqua water paWeb1 dec. 2006 · Hepatocellularity numbers were calculated from the ratio between the liver protein concentration and the protein concentration in the corresponding hepatocyte … bairedalesWeb1 dec. 2006 · Biotransformation rates measured using cryopreserved trout hepatocytes can be extrapolated to the whole animal to predict metabolism impacts on chemical bioaccumulation, and hepatocytes from male and female juvenile trout may be used interchangeably for in vitro–in vivo metabolism extrapolations. Expand 25 Highly Influenced baird & warner oak parkWeb28 jan. 2010 · Sandwich-cultured hepatocytes (SCH) are a powerful in vitro tool that can be utilized to study hepatobiliary drug transport, species differences in drug transport, transport protein regulation, drug-drug interactions, and hepatotoxicity. aqua water park bhairahawa nepalWebhepatocellular 音标：/ˌhepətəu'seljulə/ 全球发音： 生词本： 添加笔记： 有奖纠错 划词 英汉-汉英词典 词组搭配 英语例句库 全文检索 英汉-汉英词典 adj. 细胞的 词组 习惯用语 … baird wikipediaWeb美 [haɪpəseljʊ'lærɪtɪ] 是什么意思 释义 [医]细胞过多； 英英释义 hypercellularity n.the state of having abnormally many cells 学习怎么用 权威例句 hypercellularity hypercellularity Does … baird youtubeWebhepatocellularity - Wiktionary hepatocellularity English [ edit] Etymology [ edit] hepato- +‎ cellularity Noun [ edit] hepatocellularity ( uncountable ) The condition of being hepatocellular This page was last edited on 11 March 2024, at 09:48. Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. baire